Drugs of Abuse: Neurological Reviews and Protocols (Methods by John Q. Wang

By John Q. Wang

A state-of-the-art choice of up-to-date and center options for the neurological learn of substances of abuse. defined in step by step aspect via hands-on specialists, those without difficulty reproducible protocols conceal a large choice of coherent equipment for accumulating details on quantitative alterations in protein and mRNA at either tissue and mobile degrees. there are lots of equipment for detecting unmarried and a number of changes in unmarried and a number of gene expression, for interpreting the sensible roles of genes and proteins, for learning the discharge kinetics of striatal dopamine, and for the quantitative size of such neurotransmitters as acetylcholine. Insightful overview articles handle key present themes at the influence of substances of abuse at the mind.

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Brain Res. 659, 17–22. 20. Steketee, J. D. and Kalivas, P. W. (1991) Sensitization to psychostimulants and stress after injection of pertussis toxin into the A10 dopamine region. J. Pharmacol. Exp. Ther. 259, 916–924. 21. Bardo, M. , Robinet, P. , Mattingly, B. , and Margulies, J. E. (2001) Effect of 6-hydroxydopamine or repeated amphetamine treatment on mesencephalic mRNA levels for AMPA glutamate receptor subunits in the rat. Neurosci. Lett. 302, 133–136. 22. Ghasemzadeh, M. , Nelson, L. , Lu, X.

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