Ethnomedicine and Drug Discovery by M.M. Iwu, J. Wootton

By M.M. Iwu, J. Wootton

The emergence of recent infectious, persistent and drug resistant ailments have brought on scientists to seem in the direction of medicinal crops as brokers for therapy and prevention. This e-book presents an interphase among ethnomedical and ethnobotanical ways to new drug discovery and advances in biotechnology and molecular technology that has made it more and more possible to remodel conventional medications into sleek medicinal drugs. those novel techniques additionally bring up new matters and the quantity explores fiscal, moral and coverage concerns of drug improvement according to indigenous wisdom or conventional medicine.This paintings additionally positive aspects standardization and improvement of phytomedicines for significant healing symptoms, together with rising infectious ailments affecting constructing and built countries.The e-book presents state of the art info at the such a lot leading edge technology, the learn, the undefined, the industry, and the way forward for ethnomedicine and drug discovery.

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Anon. (1991) Essential drug monitor 11:15-17. 22 Ethnomedicine and drug discovery 16. Office of Technological Assessment. (1993) Pharmaceutical R & D: costs, risk and rewards. Washington DC: OTA. 17. Bohlin L, Bruhn JG. (1999) Bioassay methods in natural product research and drug development, proceeding of the Phytochemical Society of Europe. Dordrecht: Kluwer Academic, p. 201. 18. Hostettmann K (editor). (1991) Assays for bioactivity, Vol. 6. In: Dey PM, Hraborne JR, editors. Methods in plant biochemistry.

The NCI has recognized this fact for several years and has negotiated Memoranda of Understanding (MOU) with a number of source country organizations suitably qualified to perform in-country processing. In considering the continuation of its plant-derived drug-discovery program, the NCI has de-emphasized its contract collection projects in favor of expanding closer collaboration with qualified source country scientists and organizations. In establishing these collaborations, the NCI undertakes to abide by the same policies of collaboration and compensation as specified in the LOC.

The final concentration desired in a tincture can be obtained by Therapeutic agents ji'om ethnomedicine 21 Table 1 (continued) evaporation of the solvent under vacuum. Fluid extracts are produced when the solvent:plant material ratio is 2:1 to 1:1. Dry extracts: Extracts prepared from tinctures, organic extracts or hydro-alcoholic intermediates by removing the extracting solvent under vacuum. The resultant residue can be formulated as capsules, tablets or other pharmaceutical dosage forms. Solid extracts are dry extracts to which propylene glycol or liquid glycerin is added to produce a semi-solid or semi-solid viscous substance.

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